Sta,—I was interested in your correspondent's remarks about the difficulty
of causing disease in animals by the use of tobacco. This is a subject on which I have been working for some time. Part of the trouble lies in the fact that few animals really enjoy smoking —except.„ for chimpanzees (who will only touch cigars, thereby making research pro- hibitively expensive for the private individual). Guinea-pigs appear reluctant to inhale, though with patience they can be persuaded to try; rabbits, on the other hand, arc over- enthusiastic, and tend to gobble up the cigarette, paper and all.
So far in my series I have had only one case in which deleterious effects can be proved. That, interestingly enough, was in a mouse which insisted on using a cigarette holder.—Yours faithfully,
JOHN ROWAN WII.SON
83a Wimbledon Hill Road, S.W.19
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